Services
2013
D. Adams, R. Baldock, S.
Bhattacharya, A.J. Copp, M. Dickinson, N.D. Greene, R.M.
Henkelman, M. Justice, T. Mohun, S.A. Murray, E. Pauws, M.
Raess, J. Rossant, T. Weaver, D. West. Bloomsbury Report on
Mouse Embryo Phenotyping: Recommendations from the IMPC
Workshop on Embryonic Lethal Screening. Disease Models and
Mechanisms 6(3):571-579, 2013.
DOI 10.1242/dmm.011833
PMID 23519032
G.A. Anderson, M.D. Wong, J.
Yang, R.M. Henkelman. 3D Imaging, Registration, and Analysis
of the Early Mouse Embryonic Vasculature. Developmental
Dynamics 242(5):517-528, 2013.
DOI 10.1002/dvdy.23947
PMID 23417982
A.L. Conroy, K.L. Silver, K.
Zhong, M.Y. Rennie, P. Ward, J.V. Sarma, M.E. Molyneux, J.G.
Sled, J.F. Fletcher, S. Rogerson, K.C. Kain. Complement
Activation and the Resulting Placental Vascular Insufficiency
Drives Fetal Growth Restriction Associated with Placental
Malaria. Cell Host and Microbe 13(2):215-226, 2013.
DOI
10.1016/jchom.2013.01.010 PMID 23414761
J. Ellegood, B.A. Babineau,
R.M. Henkelman, J.P. Lerch, J.N. Crawley. Neuroanatomical
Analysis of the BTBR Mouse Model of Autism using Magnetic
Resonance Imaging and Diffusion Tensor Imaging. NeuroImage
70:288-301, 2013.
DOI 10.1016/j.neuroimage.2012.12.029
PMID 23275046
J.A. Gleave, J.P. Lerch, R.M.
Henkelman, B.J. Nieman. A Method for 3D Immunostaining and
Optical Imaging of the Mouse Brain Demonstrated in Neural
Progenitor Cells. PLoS One 8(8):e72039, 2013.
DOI
10.1016/j.neuroimage.2012.12.029 PMID 23275046
F. Hébert, M.
Grand'maison, M.K. Ho, J.P. Lerch, E. Hamel, B.J. Bedell.
Cortical Atrophy and Hypoperfusion in a Transgenic Mouse Model
of Alzheimer's Disease. Neurobiology of Aging 70:288-300,
2013.
DOI 10.1016/j.neurobiolaging.2012.11.022 PMID
23273599
L.B. Kelsey, A.M. Flenniken,
D. Qu, A. Funnell, R. Pearson, Y. Zhou, I. Voronina, Z.
Berberovic, G. Wood, S. Newbigging, E. Weiss, M. Wong, I.
Quach, S. Yeh, A.R. Deshwar, I.C. Scott, C. McKerlie, R.M.
Henkelman, P. Backx, J. Simpson, L. Osborne, J. Rossant, M.
Crossley, B. Bruneau, S.L. Adamson. ENU-induced Mutation in
the DNA-binding Domain of LKF3 Reveals Important Roles for
KLF3 in Cardiovascular Development and Function in Mice. PLoS
Genetics 9(7):e1003612.
DOI
10.1371/journal.pgen.1003612. PMID 23874215
L.A. Leigland, M.M. Ford,
J.P. Lerch, C.D. Kroenke. The Influence of Fetal Ethanol
Exposure on Subsequent Development of the Cerebral Cortex as
Revealed by Magnetic Resonance Imaging. Alcoholism: Clinical
and Experimental Research 37(6):924-932, 2013.
DOI
10.1111/acer.12051 PMID 23442156
L. Lindvere, R. Janik, A.
Dorr, D. Chartash, B. Sahota, J.G. Sled, B. Stefanovic.
Cerebral Microvascular Network Geometry Changes in Response to
Functional Stimulation. NeuroImage 71(1):248-259, 2013 (Cover
Illustration).
DOI 10.1016/j.neuroimage.2013.01.011
PMID 23353600.
D.K. Manning, M. Sergeev,
R.G. van Heesbeen, M.D. Wong, J.H. Oh, R.M. Henkelman, I.
Drummond, J.V. Shah, D.R. Beier. Loss of the Ciliary Kinase
Nek8 Causes Left-Right Asymmetry Defects. Journal of the
American Society of Nephrology 24(1):100-112, 2013.
DOI
10.1681/ASN.2012050490 PMID 23274954
L.K. Pacey, I.C. Xuan, S.
Guan, D. Sussman, R.M. Henkelman, Y. Chen, C. Thomsen, D.R.
Hampson. Delayed Myelination in a Mouse Model of Fragile X
Syndrome. Human Molecular Genetics 22(19):3920-3930, 2013.
DOI
10.1093/hmg/ddt246 PMID 23740941
P. Parasoglou, C. A.
Berrios-Otero, B. J. Nieman, D. H. Turnbull. High-resolution
MRI of Early Stage Mouse Embryos. NMR in Biomedicine
26(2):224-231, 2013.
DOI 10.1002/nbm.2843 PMID
22915475
A.S. Sengar, J. Ellegood,
A.P. Yiu, H. Wang, W. Wang, S.C. Juneja, J.P. Lerch, S.A.
Josselyn, R.M. Henkelman, M.W. Salter, S.E. Egan. Vertebrate
Intersectin1 is Repurposed to Facilitate Cortical Midline
Connectivity and Higher Order Cognition. Journal of
Neuroscience 33(9):4055-4065, 2013.
DOI
10.1523/JNEUROSCI.4428-12.2013 PMID 23447614
D. Sussman, M. van Eede, M.D.
Wong, S.L. Adamson, R.M. Henkelman. Effects of a Ketogenic
Diet during Pregnancy on Embryonic Growth in the Mouse.
BioMed Central Pregnancy and Childbirth 13(1):109, 2013.
DOI
10.1186/1471-2393-13-109 PMID 23656724.
M.C. van Eede, J. Scholz,
M.M. Chakravarty, R.M. Henkelman, J.P. Lerch. Mapping
Registration Sensitivity in MR Mouse Brain Images. NeuroImage
82C:226-236, 2013.
DOI
10.1016/j.neuroimage.2013.06.004 PMID 23756204
A.L. Wheeler, J.P. Lerch,
M.M. Chakravarty, M. Friedel, J.G. Sled, P.J. Fletcher, S.A.
Josselyn, P.W. Frankland. Adolescent Cocaine Exposure Causes
Enduring Macroscale Changes in Mouse Brain Structure. Journal
of Neuroscience 33(5):1797-1803, 2013.
PMID 23365219
A.L. Wheeler, A.H. Wang, C.M.
Teixeira, X. Xiong, J.P. Lerch, A.R. McIntosh, J. Parkinson,
P.W. Frankland. Identification of a Functional Connectome for
Long-term Fear Memory in Mice. PLoS Computational Biology
9(1):e1002853, 2013.
DOI 10.1371/journal.pcbi.1002853
PMID 23300432
M.D. Wong, J. Dazai, J.R.
Walls, R.M. Henkelman. Design and Implementation of a Custom
Built Optical Projection Tomographic System. PLoS One
8(9):e73491, 2013.
DOI 10.1371/journal.pone.0073491
PMID 24023880
J. Wu, YQ. Zhou, Y. Zou, R.M.
Henkelman. Evaluation of Bi-ventricular Coronary Flow Patterns
using High-Frequency Ultrasound in Mice with Transverse Aortic
Constriction. Ultrasound in Biology and Medicine
39(11):2053-2065, 2013.
DOI
10.1016/j.nltrasmedbio.2013.04.022 PMID 23932279
2012
S.A. Bainbridge, A. Minhas,
K.J. Whiteley, D. Qu, J.G. Sled, J.C.P. Kingdom, S.L. Adamson.
Effects of Reduced Gcm1 Expression of Trophoblast Morphology,
Feto-placental Vascularity and Pregnancy Outcomes in Mice.
Hypertension 59(3):732-739, 2012.
DOI
10.1161/HYPERTENSIONAHA.111.183939 PMID 22275534
C.A. Berrios-Otero, B.J.
Nieman, P. Parasoglou, D.H. Turnbull. In Utero Phenotyping of
Mouse Embryonic Vasculature with MRI. Magnetic Resonance in
Medicine 67(1):251-257, 2012.
DOI 10.1002/mrm.22991
PMID 21590728
L.S. Cahill, C.L.
Laliberté, J. Ellegood, S. Spring, J.A. Gleave, M.C.
van Eede, J.P. Lerch, R.M. Henkelman. Preparation of Fixed
Mouse Brains for MRI. NeuroImage 60(2):933-939, 2012.
DOI
10.1016/j.neuroimage.2012.01.100 PMID 22305951
M.M. Chakravarty, D. Felsky,
M. Tampakeras, J.P. Lerch, B. Mulsant, J. Kennedy, A.
Voineskos. DISC1 and striatal volume: a potential risk
phenotype for mental illness. Frontiers in Neuropsychiatric
Imaging and Stimulation 3:57, 2012.
DOI
10.3389/fpsyt.2012.00057 PMID 22723785.
L.V. Chinta, L. Lindvere, A.
Dorr, B. Sahota, J.G. Sled, B. Stefanovic. Quantitative
Estimates of Stimulation-induced Perfusion Response using
Two-photon Fluorescence Microscopy of Cortical Microvascular
Networks. NeuroImage 61(3):517-524, 2012.
DOI
10.1016/j.neuroimage.2012.04.009 PMID 22521258
B.P. Chugh, J. Bishop, Y-Q.
Zhou, J. Wu, R.M. Henkelman, J.G. Sled. A Robust Method for 3D
Arterial Spin Labeling in Mice. Magnetic Resonance in Medicine
68(1):98-106, 2012.
DOI 10.1002/mrm.23209 PMID
22102489
J. Ellegood, R.M. Henkelman, J.P. Lerch. Magnetic Resonance
Imaging as a Tool for the Study of Mouse Models of Autism.
Autism S1:008, 2012. www.omicsgroup.org/journals/auohome.php
DOI 10.4172/2165-7890.S1-008
J. Ellegood, R.M. Henkelman,
J.P. Lerch. Neuroanatomical Assessment of the Integrin β3
Mouse Model related to Autism and Serotonin System using High
Resolution MRI. Frontiers of Psychiatry Translational Imaging
Genetics 3:37, 2012.
DOI 10.3389/psyt.2012.00037 PMID
22557981
L.M. Gazdzinski, K. Cormier,
F.G. Lu, J.P. Lerch, C.S. Wong, B.J. Nieman. Radiation-induced
Alterations in Mouse Brain Development Characterized by MRI.
International Journal of Radiation Oncology Biology Physics
84(5):e631-e638, 2012.
DOI
10.1016/j.ijrobp.2012.06.053 PMID 22975609
J.A. Gleave, M.D. Wong, J.
Dazai, M. Altaf, R.M. Henkelman, J.P. Lerch, B.J. Nieman.
Neuroanatomical Phentoyping of the Mouse Brain with
Three-dimensional Autofluorescence Imaging. Physiological
Genomics 44(15):778-785, 2012.
DOI
10.1161/physiolgenomics.00055.2012 PMID 22718750
J.P. Lerch, L. Gazdzinski, J.
Germann, J.G. Sled, R.M. Henkelman, B.J. Nieman. Wanted Dead
or Alive? The Tradeoff between In-Vivo versus Ex-vivo MR Brain
Imaging in the Mouse. Frontiers in Neuroinformatics 6:6, 2012.
DOI 10.3389/fninf.2012.00006 PMID22470335
A. Mansouri, W. Min, C.J.
Cole, S.A. Josselyn, J.T. Henderson, M. van Eede, R.M.
Henkelman, C. Ackerley, E. Grunebaum, C.M. Roifman. Cerebellar
Abnormalities in Purine Nucleoside Phosphorylase Deficient
Mice. Neurobiology of Disease 47(2):201-209, 2012.
DOI
10.1016/j.nbd.2012.04.001 PMID 22521465
K. Marcinko, T. Parsons, J.P.
Lerch, J.G. Sled, B. Sakic. Effects of Prolonged Treatment
with Memantine in the MRL Model of CNS Lupus. Clinical and
Experimental Neuroimmunology 3(3): 116-128, 2012.
DOI
10.1111/j.1759-1961.2012.00032.x
B.J. Nieman, M.C. Blank, B.B.
Roman, R.M. Henkelman, K.J. Millen. If the Skull Fits:
Magnetic Resonance Imaging and Microcomputed Tomography for
Combined Analysis of Brain and Skull Phenotypes in the Mouse.
Physiological Genomics44:992-1002, 2012.
DOI
10.1152/physiogenomics.00093.2012 PMID 22947655
M.Y. Rennie, J. Detmar, K.J.
Whiteley, A. Jurisicova, S.L. Adamson, J.G. Sled. Expansion of
the Fetoplacental Vasculature in Late Gestation is Strain
Dependant in Mice. American Journal of Physiology-Heart and
Circulatory Physiology 302(6):H1261-1273, 2012.
DOI
10.1152/ajpheart.00776.2011 PMID 22268107
G. Winocur, M. Henkelman, M.
Wojtowicz, H. Zhang, M. Binns, I. Tannock. The Effects of
Chemotherapy on Cognitive Function in a Mouse Model: A
Prospective Study. Clinical Cancer Research 18(11):3112-3121,
2012.
DOI 10.1158/10788-0432.CCR-12-0060 PMID 22467680
J. Yang, H. Noyan-Ashraf, A.
Meissner, J. Voiglaender-Bolz, J.T. Kroetsch, W. Foltz, D.
Jaffray, A. Kapoor, A. Momen, S.P. Hexmier, H. Zhang, M. van
Eede, M. Henkelman, S.G. Matthews, D. Lidington, M. Husain,
S-S. Bolz. Proximal Cerebral Arteries Develop Myogenic
Responsiveness in Heart Failure Via TNFα-dependent
Activation of S1P Signaling. Circulation 126(2):196-206, 2012.
DOI 10.1161/CIRCULATIONAHA.111.039644 PMID 22668972
M.D. Wong, A.E. Dorr, J.R.
Walls, J.P. Lerch, R.M. Henkelman. A Novel 3D Mouse Embryo
Atlas Based on Micro-CT. Development 139(17):3248-3256, 2012.
DOI 10.1242/dev.082016 PMID 22872090
2011
K.G. Akers, S.A. Kushner,
A.T. Leslie, L. Clarke, D. van der Kooy, J.P. Lerch, P.W.
Frankland. Fetal Alcohol Exposure Leads to Abnormal Olfactory
Bulb Development and Impaired Odor Discrimination in Adult
Mice. Molecular Brain 4:29, 2011.
DOI
10.1186/1756-6606-4-29
L. Baghdadi, M. Zamyadi, J.G.
Sled, J.E. Schneider, S. Bhattacharya, R.M. Henkelman, J.P.
Lerch. Semi-Automatic Segmentation of Multiple Mouse Embryos
in MR Images. BMC Bioinformatics 12(1):237, 2011.
www.biomedcentral.com/1471-2105/12/237
DOI 10.1186/1471-2105-12-237 PMID 21679425
M.C. Blank, I. Grinberg, E.
Aryee, C. Laliberte, V.V. Chizhikov, R.M. Henkelman, K.J.
Millen. Multiple Cerebellar Developmental Programs Are Altered
by Loss of Zic1 and Zic4 to Cause Dandy-Walker Malformation
Cerebellar Pathogenesis. Development 138(6):1207-1216, 2011.
DOI 10.1242/dev.054114 PMID 21307096
J.B. Carroll, J.P. Lerch, S.
Franciosi, A. Spreeuw, N. Bissada, R.M. Henkelman, M.R.
Hayden. Natural History of Diseases in the YAC128 Mouse
Reveals a Discrete Signature of Early Pathology in HD.
Neurobiology of Disease 43(1):257-265, 2011.
DOI
10.1016/j.nbd.2001.03.018 PMID 21458571
J.B. Carroll, A.L. Southwell,
R.K. Graham, J.P. Lerch, D.E. Ehrnhoefer, L-P. Cao, W-N.
Zhang, Y. Deng, N. Bissada, R.M. Henkelman, M.R. Hayden. Mice
Lacking Caspase-2 are Protected from Behavioral Changes, But
Not Pathology, in the YAC128 Model of Huntington Disease.
Molecular Neurodegeneration 6:59, 2011.
DOI
10.1186/1750-1326-6-59 PMID 21854568
X.J. Chen, B.J. Nieman. Mouse
phenotyping with MRI. Methods in Molecular Biology
771:595-631, 2011.
DOI 10.1007/978-1-61779-219-9_31
PMID 21874500
J. Ellegood, J.P. Lerch, R.M.
Henkelman. Brain Abnormalities in a Neuroligin3 R451C Knockin
Mouse Model Associated with Autism. Autism Research
4(5):368-376, 2011.
DOI 10.1002/aur.215 PMID
21882360197.
Y. Hoi, Y-Q. Zhou, X. Zhang,
R.M. Henkelman, D.A. Steinman. Correlation between Local
Hemodynamics and Lesion Distribution in Novel Aortic
Regurgitation Murine Model of Atherosclerosis. Annals of
Biomedical Engineering 39(5):1414-1422, 2011.
DOI
10.1007/s10439-011-0255-z PMID 21279441
G. Horev, J. Ellegood, J.P.
Lerch, E. Son, L. Muthuswamy, H. Vogel, A.M. Krieger, A. Buja,
R.M. Henkelman, M. Wigler, A.A. Mills. Dosage-dependent
Phenotype in Models of 16p11.2 Lesions Found in Autism. PNAS
108(41):17076-17081, 2011.
PMID 21969575
W. Huang, Z. Zhou, S. Asrar,
M. Henkelman, W. Xie, Z. Jia. p21-Activated Kinases 1 and 3
control Brain Size through Coordinating Neuronal Complexity
and Synaptic Properties. Molecular and Cellular Biology
31(3):388-403, 2011.
DOI 10.1128/MCB.00969-10 PMID
21115725
M. Jeansson, A. Gawlik, G.
Anderson, C. Li, D. Kerjaschki, R.M. Henkelman, S.E. Quaggin.
Angiopoietin-1 is Essential in Mouse Vasculature during
Development and in Response to Injury. Journal of Clinical
Investigation 121(6):2278-2289, 2011.
DOI
10.1172/JCI46322 PMID 21606590
M. Jerkic, M.G. Kabir, A.
Davies, L.X. Yu, B.A.S. McIntyre, N.W. Husain, M. Enomoto, V.
Sotov, M. Husain, M. Henkelman, J. Belik, M. Letarte.
Pulmonary Hypertension in Adult Alk1 Heterozygous Mice Due to
Oxidative Stress. Cardiovascular Research 92(3):375-384, 2011.
DOI 10.1093/cvr/cvr232 PMID 21859819
J.J. Kim, P.S. Gill, L.
Rotin, M. van Eede, M. Henkelman, C-C. Hui, N.D. Rosenblum.
Suppressor of Fused Controls Mid-Hindbrain Patterning and
Cerebellar Morphogenesis Via GL13 Repressor. Journal of
Neuroscience 31(5):1825-1836, 2011.
PMID 21289193
J.P. Lerch, J.G. Sled, R.M.
Henkelman. MRI Phenotyping of Genetically Altered Mice.
Methods in Molecular Biology 711:349-361, 2011.
PMID
21279611
J.P. Lerch, A.P. Yiu, A.
Martinez-Canabal, T. Pekar, V.D. Bohbot, P.W. Frankland, R.M.
Henkelman, S.A. Josselyn, J.G. Sled. Maze Training in Mice
Induces MRI Detectable Brain Shape Changes Specific to the
Type of Learning. NeuroImage 54(3):2086-2095, 2011.
DOI 10.1016/j.neuroimaging.2010.09.068 PMID 20932918
P. Mohseni, H-K. Sung, A.J.
Murphy, C.L. Laliberte, H-M. Pallari, R.M. Henkelman, J.
Georgiou, G. Xie, S.E. Quaggin, P.S. Thorner, J.E. Eriksson,
A. Nagy. Nestin is not Essential for Development of the CNS
But Required for Dispersion of Acetylcholine Receptor Clusters
at the Area of Neuromuscular Junctions. Journal of
Neuroscience 31(32):11547-11552, 2011.
DOI
10.1523/JNEUROSCI.4396.10.2011 PMID 21832185
E.E. Mueller, A. Momen, S.
Massé, Y-Q. Zhou, J. Liu, P.H. Backx, R.M. Henkelman,
K. Nanthakumar, D.J. Stewart, M. Husain. Electrical Remodeling
Precedes Heart Failure in an Endothelin-1-induced Model of
Cardiomyopathy. Cardiovascular Research 89(3):623-633, 2011.
DOI 10.1093/cvr/cvq351 PMID 21062919
B.J. Nieman, M.D. Wong, R.M.
Henkelman. Genes into Geometry: Imaging for Mouse Development.
Current Opinion in Genetics and Development 21(5):638-646,
2011.
DOI 10.1016/j.gde.2011.08.008 PMID 21907568
M.Y. Rennie, J. Detmar, K.
Whiteley, J. Yang, A. Jurisicova, S.L. Adamson, J.G. Sled.
Vessel Tortuousity and Reduced Vascularization in the
Fetoplacental Arterial Tree after Maternal Exposure to
Polycyclic Aromatic Hydrocarbons. American Journal of
Physiology-Heart and Circulatory Physiology 300(2):H675-H684,
2011.
DOI 10.1152/ajpheart.00510.2010 PMID 21148768.
R.R. Singaraja, K. Huang,
S.S. Sanders, A. Milnerwood, R. Hines, J. Lerch, S. Franciosi,
R. Drisdel, K. Vaid, F.B. Young, C. Doty, J. Wan, N. Bissada,
R.M. Henkelman, W.N. Green, N.G. Davis, L.A. Raymond, M.R.
Hayden. Altered Palmitoylation and Neuropathological Deficits
in Mice Lacking HIP14. Human Molecular Genetics
20(20):3899-3909, 2011.
DOI 10.1093/hmg/ddr308 PMID
21775500
J.K. Takeuchi, X. Lou, J.M.
Alexander, H. Sugizaki, P. Delgado-Olguin, A.K. Holloway, A.D.
Mori, J.N. Wylie, C. Munson, Y. Zhu, Y.Q. Zhou, R.F. Yeh, R.M.
Henkelman, R.P. Harvey, D. Metzger, P. Chambon, D.Y. Stainier,
K.S. Pollard, I.C. Scott, B.G. Bruneau. Chromatin Remodeling
Complex Dosage Modulates Transcription Factor Function in
Heart Development. Nature Communications 2:187, 2011.
DOI 10.1038/ncomms1187(2011) PMID 2130451
A.K.Y. Tsui, P.A. Marsden,
C.D. Mazer, S.L. Adamson, M. Henkelman, D. Wilson, S.P.
Heximer, M. El-beheiry, N. Dattani, K. Chen, G.M.T. Hare.
Priming of Hypoxia Inducible Factor by Neuronal Nitric Oxide
Synthase-derived Nitric Oxide is Essential for Adaptive
Responses to Severe Anemia. PNAS 108(42):17544-17549, 2011.
DOI 10.1073/pnas.1114026108 PMID 21976486
X. Yu, A. Suderov, K. U.
Szulc, B. J. Nieman, D. Abdollahian, N. Bhatia, A. K. Lalwani,
A. L. Joyner, D. H. Turnbull. Morphological and Functional
Midbrain Phenotypes of Fgf17 Mutant Mice Revealed by
Mn-enhanced MRI. NeuroImage 56(3):1251-1258, 2011.
DOI 10.1016/j.neuroimage.2011.02.068 PMID 21356319
S-S. Zhang, K-H. Kim, A. Rosen, J.W. Smyth,
R. Sakuma, P. Dalgado-Olguin, M. Davis, N.C. Chi, V.
Puviindran, N. Gaborit, T. Sukonnik, J.N. Wylie, K.
Brand-Arzamendi, G. Farman, J. Kim, R.A. Rose, P.A. Marsden,
Y. Zhu, Y-Q. Zhou, L. Miquerol, R.M. Henkelman, D.Y.R.
Stainier, R.M. Shaw, C-C. Hui, B.G. Bruneau, P.H. Backx.
Iroquois Homeobox Gene 3 Establishes Fast Conduction in the
Cardiac His-Purkinje Network. Proceedings of the National
Academy of Science USA 108(33):13576-13581, 2011.
DOI
10.1073/pnas.1106911108 PMID 21825130
2010
X.J. Chen, S. Maheswaran, D. Ruckert, R.M. Henkelman. Image
Registration of Whole-body Mouse MRI. 2010 7th IEEE
International Symposium on Biomedical Imaging: From Nano to
Macro, pp. 1063-1064, 2010.
DOI
10.1109/ISBI.2010.5490174
L. Coultas, E. Nieuwenhuis,
G.A. Anderson, R.M. Henkelman, C-C. Hui, J. Rossant. Hedgehog
Regulates Blood Vascular Development through VEGF Dependent
and Independent Mechanisms. Blood 116(4):653-660, 2010.
DOI 10.1182/blood-2009-12-256644 PMID 20339091
J. Dazai, S. Spring, L.S. Cahill, R.M. Henkelman.
Multiple-Mouse Neuroanatomical Magnetic Resonance Imaging
(Video Article). Journal of Visualized Experiments (JoVE),
2010. http://www.jove.com/index/Details.stp?ID=2497.
DOI 10.3791/2497
J. Ellegood, L.K. Pacey, D.R.
Hampson, J.P. Lerch, R.M. Henkelman. Anatomical Phenotyping in
a Mouse Model of Fragile X Syndrome with Magnetic Resonance
Imaging. NeuroImage 53(3):1023-1029, 2010.
DOI
10.1016/j.neuromage.2010.03.038 PMID 20304074
F. Fouladkou, C. Lu, C.
Jiang, L. Zhou, Y. She, J.R. Walls, H. Kawabe, N. Brose, R.M.
Henkelman, A. Huang, B.G. Bruneau, D. Rotin. The Ubiguitin
Ligase NEDD4-1 is Required for Heart Development and is a
Suppressor of Thrombospondin-1. Journal of Biological
Chemistry 285(9):6770-6780, 2010.
DOI
10.1074/jbc.M109.082347 PMID 20026598
R.M. Henkelman. Systems
Biology through Mouse Imaging Centers: Experience and New
Directions. Annual Review of Biomedical Engineering
12:143-166, 2010.
DOI
10.1146/annurev-bioeng-070909-105343 PMID 20415591
A. Khmelinskii, M. Baiker, X.J. Chen, J. Reiber, R.M.
Henkelman, B.P.F. Lelieveldt. Atlas-based organ and bone
approximation for ex-vivo µMRI mouse date: a pilot study.
2010 7th IEEE International Symposium on Biomedical Imaging:
From Nano to Macro, pp. 1197-1200, 2010.
DOI
10.1109/ISBI.2010.5490209
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PMID 20691877
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Genetic Deletion or Pharmacological Inhibition of Dipeptidyl
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Spontaneous Adult-onset Pulmonary Arterial Hypertension
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Egan. Lunatic Fringe-mediated Notch Signaling is Required for
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Heterotypic Cardiac Isografts using Ultrasound Biomicroscopy.
Ultrasound in Medicine and Biology 33(6):870-879, 2007.
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2006
J. Bishop, A. Feintuch, J.
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Lipina, J.C. Roder, S.L. Ackerman, R.M. Henkelman. InVivo
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X.J. Chen, R.M. Henkelman. Rapid phenotyping of mice with
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X.J. Chen, N. Kovacevic, N.J.
Lobaugh, J.G. Sled, R.M. Henkelman, J.T. Henderson.
Neuroanatomical Differences between Mouse Strains as Shown by
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J.G. Sled. Presentation of 3D Isotropic Imaging Data for
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56(6):1371-1374, 2006.
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C. Du, Y-Q, Zhou, M. Henkelman, P.S. Mongroo, A. Lau, H.
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Integrin-Linked Kinase Expression is Elevated in Human Cardiac
Hypertrophy and Induced Hypertrophy in Transgenic Mice.
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M. Marxen, C. Paget, L.X. Yu,
R.M. Henkelman. Estimating Perfusion using MicroCT to Locate
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B.J. Nieman, A.M. Flenniken,
S.L. Adamson, R.M. Henkelman, J.G. Sled. Anatomical
Phenotyping in the Brain and Skull of Mutant Mice by Magnetic
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Shannon, D. Herlyn, D. Kaplan, R.M. Henkelman, D.H. Gutmann,
A. Guha. High-Grade Glioma Formation Results from Postnatal
Pten Loss or Mutant Epidermal Growth Factor Receptor
Expression in a Transgenic Mouse Glioma Model. Cancer Research
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2005
R. Behin, J. Bishop, R.M.
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Henkelman. Analysis of micro-vasculature in whole kidney
specimens using micro-CT. 40 th Annual Meeting of the SPIE,
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Erdemir, H. Lickert, J.R. Walls, R.M. Henkelman, J. Rossant,
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D.J. Dumont. Angiopoietin-1 Causes Reversible Degradation of
the Portal Microcirculation in Mice: Implications for
Treatment of Liver Disease. American Journal of Pathology
165(3):889-899, 2004.
PMID 15331413
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N.A. Bock, N.B. Konyer, R.M.
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Davidson B. Qian, J.G. Sled, R.M. Henkelman, A. Guha.
High-Resolution Longitudinal Screening with Magnetic Resonance
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5(6):546-554, 2003.
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48:3225-3237, 2003.
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N. Kovacevic, G. Hamarneh, M.
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M. Marxen, R.M. Henkelman.
Branching Tree Model with Fractal Vascular Resistance Explains
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Physiology Heart Circulation and Physiology 284:H1848-H1857,
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W.R. van Furth, S. Laughlin,
M.D. Taylor, B. Salhia, T. Mainprize, M. Henkelman, M.D.
Cusimano, C. Ackerley, J.T. Rutka. Imaging of Murine Brain
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of Neurological Science 30:326-332, 2003.
PMID
14672264
Y.Q. Zhou, F.S. Foster, R.
Parkes, S.L. Adamson. Developmental Changes in Left and Right
Ventricular Diastolic Filling Patterns in Mice. American
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Y.Q. Zhou, F.S. Foster, D.W.
Qu, M. Zhang, K.A. Harasiewicz, S.L. Adamson. Applications for
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F.S. Foster, M.Y. Zhang, Y.Q.
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